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Image Credit Header image: Artwork by Professor Lubaina Himid, CBE. Photo: @Denise Swanson
Khan, Zahra R., Welsby, Philip J., Stasik, Izabela
ORCID: 0000-0002-7756-4731 and Hayes, Joseph
ORCID: 0000-0002-7745-9616
(2027)
In silico screening for CDK5 inhibitors leads to SAR analysis of flavonoids, three diverse inhibitor scaffolds and fisetin demonstrating potent in vitro glioblastoma effects.
Journal of Molecular Structure, 1381
(3).
p. 147607.
ISSN 0022-2860
Khan, Zahra Rafiqa, Welsby, Philip J., Stasik, Izabela
ORCID: 0000-0002-7756-4731 and Hayes, Joseph
ORCID: 0000-0002-7745-9616
(2025)
Computationally Motivated Discovery of Biogenic Compounds with Potent CDK9 Inhibition and In Vitro Effects against Glioblastoma.
ACS Chemical Neuroscience, 16
(20).
pp. 4086-4100.
ISSN 1948-7193
Khan, Zahra Rafiqa, Welsby, Philip J., Stasik, Izabela
ORCID: 0000-0002-7756-4731 and Hayes, Joseph
ORCID: 0000-0002-7745-9616
(2024)
Discovery of Potent Multikinase Type-II Inhibitors Targeting CDK5 in the DFG-out Inactive State with Promising Potential against Glioblastoma.
Journal of Medicinal Chemistry, 67
(9).
pp. 7539-7552.
ISSN 0022-2623
Mathomes, Rachel Thelma
ORCID: 0000-0002-1079-8509, Koulas, Symeon M., Tsialtas, Ioannis, Stravodimos, George, Welsby, Philip J., Psarra, Anna-Maria G., Stasik, Izabela
ORCID: 0000-0002-7756-4731, Leonidas, Demetres D. and Hayes, Joseph
ORCID: 0000-0002-7745-9616
(2023)
Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its’ potential against glioblastoma in cellular models.
Chemico-Biological Interactions, 382
.
ISSN 0009-2797
Welsby, Philip J.
ORCID: 0000-0002-2110-8198, Rowan, Michael J. and Anwyl, Roger
(2009)
Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus.
European Journal of Neuroscience, 29
(1).
pp. 65-75.
ISSN 0953816X